Portions of this document last updated: Feb. 01, 2023. Nevirapine can cause serious, life-threatening side effects. Your doctor may increase your dose as needed. Last medically reviewed on September 7, 2021. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Keep taking this medication even if you feel well. However, current knowledge on pharmacodynamic and pharmacokinetic properties of penicillins does not support this recommendation. If you take these drugs together, your doctor should monitor the level of digoxin in your body. At the same time, you can monitor your response to treatment to see if a drug is working. Call your doctor for medical advice about side effects. Your doctor will tell you which of these are most important for you. They cant hurt your medication. Many people using this medication do not have serious side effects. Take nifedipine exactly as prescribed by your doctor. You should refer to the prescribing information for nifedipine for a complete list of interactions. This content does not have an English version. Medicines that interact with nifedipine may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with nifedipine. Follow all directions on your prescription label. Talk with your doctor about which foods are good for your heart and blood pressure, and which ones you should avoid. (2021). Obstetrics and Gynecology 24 years experience. Talk to your doctor if you develop edema, angina pain, are pregnant or become pregnant, or develop any other worrying side effects. There are many factors to consider, he says, such as: Your medication regimen should be personalized for you based upon a discussion with your physician, says Bhusri. Some products have ingredients that could raise your heart rate or blood pressure. Your doctor can tell you where to buy this device and how to use it. Avoid eating grapefruit or drinking grapefruit juice while being treated with this medication unless your doctor instructs you otherwise. Dont chew, crush, or divide them. These include liver problems and severe skin rash and allergic reactions. In Canada - Call your doctor for medical advice about side effects. To provide you with the most relevant and helpful information, and understand which Nifedipine is an oral medication used to treat hypertension (high blood pressure). The starting dose is 30 mg or 60 mg by mouth once per day. Nifedipine immediate-release capsules are available as the brand-name drug Procardia. Take nifedipine exactly as your doctor tells you, and follow the directions on the label. privacy practices. If you take too much: You could have dangerous levels of the drug in your body. Low blood pressure or low heart rate. Nifedipine is used to lower blood pressure in people with hypertension. Medically reviewed by Sanjai Sinha, MD. It works by relaxing blood vessels so blood can flow more easily. Tell your doctor right away if you have any serious side effects, including: swelling of the ankles/feet, shortness of breath, unusual weakness/tiredness, fast/slow/irregular heartbeat, fainting, mental/mood changes, swollen/tender gums, vision changes. Follow the directions on your medicine label about taking this medication with or without food. Talk to your pharmacist for more details. other information we have about you. Copyright 1996-2023 Cerner Multum, Inc. This usually means you do not need to take them as often. You may opt-out of email communications at any time by clicking on Properly discard this product when it is expired or no longer needed. Take the nifedipine packet or leaflet inside it plus any remaining medicine with you. Do not use a kitchen teaspoon as it will not measure the right amount. As a result, less pressure is built up and your heart does not have to work as hard to pump blood. It has many uses in cardiology and is even used in pregna. Your doctor may increase your dose as needed. Should you be taking your blood pressure medication at bedtime rather than in the morning? Taking them on an empty stomach can increase your risk of stomach problems. It works by relaxing the muscles of your heart and blood vessels. Do not take nifedipine with any grapefruit juice or other products made using grapefruit (such as marmalade). To improve absorption, it is usually recommended that penicillin is given on an empty stomach. ChildrenUse and dose must be determined by your doctor. Severe chest pain develops in some cases (and . Follow the directions on your medicine label about taking this medication with or without food. Dr. Kim Williams, the head of the division of cardiology at Rush University Medical Center and past president of the American College of Cardiology, says he feels its too soon to begin recommending that all patients take their medications at bedtime. Nifedipine oral tablet doesnt cause drowsiness. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Many also feel that it is easier to remember morning medications. You may need to use an insulated bag with a cold pack to keep it cold. Nifedipine should not be used to rapidly drop blood pressure as this may be fatal and it should not be taken with grapefruit juice or grapefruit products. These may include: Vomiting. Talk to your doctor if you want to stop taking nifedipine. You may need to use blood pressure medication for the rest of your life. Our website services, content, and products are for informational purposes only. Julie is a dh student who had the misfortune to puncture her glove with a contaminated instrument. Follow your doctor's orders or the directions on the label. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Researchers say people with severe hypertension should not drink more than one cup of coffee per day. Taking certain antibiotics with nifedipine can cause higher levels of nifedipine in your body. Typically, these symptoms occur toward the end of meals or soon after meals are finished. Selected from data included with permission and copyrighted by First Databank, Inc. Although no "rebound" effect has been seen on discontinuation of nifedipine, it is suggested that the dose be withdrawn gradually under a doctor's supervision. other information we have about you. swelling of the breasts or breast soreness in both females and males. This survey is being conducted by the WebMD marketing sciences department. It will depend on how old your child is and how much they weigh. The capsules are used to treat angina (chest pain). If you miss doses or dont take the drug on schedule: Your medication may not work as well or may stop working completely. Your doctor may suggest that you monitor your blood pressure at home. Talk to your doctor or pharmacist about lifestyle changes that might benefit you. This raises your risk of side effects from nifedipine. Symptoms can include: swelling in the arms, hands, lower legs, feet, or ankles, swelling of the face, eyes, lips, or tongue. You may need to use blood pressure medication for the rest of your life. If you're not sure, check with your doctor or pharmacist. Revision date: August 28, 2022. Some medicines need to be taken "before food" or "on an empty stomach". It's just the outer shell of the tablet which your body has not digested. If the starting dose is not working well enough (your blood pressure does not come down enough, or you are still getting symptoms), you may need to increase your dose. This may cause the amount of nifedipine in your blood to be too high. How to tell if the drug is working: If youre taking this drug to treat high blood pressure, your blood pressure level should go down. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. For people with a history of gastrointestinal blockage: There have been rare reports of gastrointestinal blockage with use of the brand-name drug Procardia XL. However, when introducing a new drug to your system, there's always the chance of adverse effects. Nifedipine is in a class of medications called calcium-channel blockers. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Lifestyle changes such as stress reduction programs, exercise, and dietary changes may increase the effectiveness of this medicine. If youre taking a beta-blocker and your doctor has you stop taking it before starting nifedipine, the beta-blocker should be tapered slowly. This can help keep levels of this drug from building up too much in your body. This can increase your risk of side effects from nifedipine. Take this medication by mouth on an empty stomach, usually once daily or as directed by your doctor. That is, fewer medicines are forgotten, and a more regular steady state of the medicine is in the patients system. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use nifedipine only for the indication prescribed. Nifedipine oral tablet is a prescription drug thats available as the brand-name drugs Adalat CC, Afeditab CR, and Procardia XL. Nifedipine belongs to a class of drugs called calcium channel blockers. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. And you don't . Some supplements and medications can also interfere with the way . The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Taking it with food may help to reduce upset stomach. Your blood pressure may need to be carefully monitored during the initial administration and titration of nifedipine. What you eat and drink can cause harmful effects when mixed with certain drugs. Symptoms can include: If you have these symptoms, call 911 or go to the nearest emergency room. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. FDA-approved indications include chronic stable angina, hypertension. There are other drugs available to treat your condition. He or she may need to adjust your dose of Synthroid. For women who are breastfeeding: Nifedipine may pass into breast milk and can cause serious side effects in a child who is breastfed. stomach discomfort, upset, or pain. Drug information provided by: IBM Micromedex. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Medically reviewed by Carmen Fookes, BPharm. Nifedipine capsules (Procardia) should not be taken within the first week or two after a heart attack. Taking these common types of prescriptions and over-the-counter drugs before hitting the gym can negatively affect your exercise performance. "Nausea is one of the most common side effects of medications we hear about," says Joanne Doyle Petrongolo, a pharmacist at Harvard-affiliated Massachusetts General Hospital. Call your doctor if you become pregnant while taking this drug. What conditions does Nifedipine ER oral treat? In the US - Call your doctor for medical advice about side effects. For this drug to work well, a certain amount needs to be in your body at all times. Also, since many medications cause urination, people may prefer to take them early in the day. Follow your doctor's instructions carefully. Copyright 1996-2023 Drugs.com. Always carry the original prescription-labeled box with you. Your doctor may start you on a lowered dose or a different medication schedule. Available for Android and iOS devices. All rights reserved. Dont take this drug again if you have ever had an allergic reaction to it before. Skip the missed dose if it is almost time for your next scheduled dose. Its also used to treat vasospastic angina (chest pain due to a spasm in arteries around the heart) or chronic stable angina (chest pain that occurs with activity or stress). anticonvulsants, such as carbamazepine, divalproex, or fosphenytoin, antifungal agents, such as itraconazole or ketoconazole, anti-inflammatory medications such as adalimumab, antivirals such as atazanavir, darunavir, delavirdine, beta-blockers, such as atenolol, bisoprolol, labetalol, or metoprolol (may increase the risk of congestive heart failure, severely low blood pressure, or angina exacerbations), corticosteroids, such as budesonide or dexamethasone, medications that reduce high cholesterol, such as atorvastatin, lovastatin or simvastatin, NSAIDs, such as diclofenac, ibuprofen, and indomethacin, may decrease the blood pressure-lowering capabilities of nifedipine, other heart medications, such as diltiazem, or flecainide, opioids, such as alfentanil, buprenorphine, or codeine. You may need to buy a blood pressure monitor to check your blood pressure at home. Heres how you can reduce your risk during the winter months. Copyright 2023 IBM Watson Health. Cardinal Health. Remember to use it at the same time each day. For instance, if you are taking medications for diabetes and your blood sugar remains normal, there is a good . Other medications can affect the removal of nifedipine from your body, which may affect how nifedipine works. Discuss the use of grapefruit products with your doctor. We comply with the HONcode standard for trustworthy health information. If it is near the time of the next dose, skip the missed dose. Common side effects may include: swelling; Find out how to avoid these four common food-drug interactions. As we age, however, we may develop a blood pressure pattern called non-dipping. In some cases, they may not be available in every strength or form as the brand-name version. Stopping suddenly may make your condition worse. Get someone else to drive you or call for an ambulance. Before taking nifedipine, tell your doctor if you have kidney or liver disease, a blockage in your digestive tract (stomach or intestines), a history of stomach surgery, coronary artery disease, underactive thyroid, diabetes, or congestive heart failure. In the study, the researchers followed 19,084 patients with high blood pressure for a median of 6 years. Levothyroxine is the second-most-prescribed drug in the U.S., with more than 102 million prescriptions in 2019. Historically, people were advised to take their pill first thing in the morning, on an empty stomach, and wait at least an hour before having breakfast. You may report side effects to Health Canada at 1-866-234-2345. These drugs include: Taking the antibiotic rifampin can decrease the levels of nifedipine in your body. Nifedipine is used to treat hypertension (high blood pressure) and angina (chest pain). 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Last updated on Nov 28, 2022. Should I avoid certain foods while taking Nifedipine ER oral? Do not change tablet strengths or use a different number of tablets for your dose without consulting your doctor or pharmacist. This dosage information is for nifedipine oral tablet. The capsules are available as the brand-name drug. Review/update the Disclaimer: Our goal is to provide you with the most relevant and current information. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. High blood pressure often has no symptoms. WebMD does not provide medical advice, diagnosis or treatment. Dizziness may increase your risk of falls. As a result, your heart receives more blood and oxygen. Keep all medications away from children and pets. Extended-release products work like a little pump as they pass through the GI tract, slowly releasing the medication contained inside the tablet shell over a certain time period. Tell your doctor if you are breast-feeding a baby. Statins & grapefruitor maybe not. trouble concentrating. To decide the correct dose for you, your doctor will check your blood pressure. the unsubscribe link in the e-mail. The exact way nifedipine works in angina is not known; however, experts believe it helps prevent spasm of the coronary artery and reduces how hard the heart has to work to pump blood around the body, lowering its oxygen requirements. Your doctor may increase your dose as needed. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk with your doctor about which form is right for you. However, green tea doesn't appear to have the. The drug form used depends on the condition it is treating. You may also want to avoid food and drinks known to irritate the stomach, such as alcohol and spicy dishes. Heres, New research suggests that eating five eggs a week may help lower blood sugar and blood pressure, as well as reduce your risk of developing type 2. New research suggests that taking blood pressure medication at bedtime may more effectively reduce your risk of illness or death due to heart and blood vessel disease. Nifedipine oral tablet can interact with other medications, vitamins, or herbs you may be taking. You should check with your doctor before changing your diet. This medication must be taken regularly to be . Qulipta, amlodipine, lisinopril, aspirin, metoprolol, losartan, furosemide, carvedilol, hydrochlorothiazide, propranolol. May be taken with or without food. Nifedipine is also used to alleviate angina-caused chest pain. The bottom line. If you are also taking a beta-blocker (atenolol, carvedilol, labetalol, metoprolol, nadolol, nebivolol, propranolol, sotalol, and others) you should not stop using the beta-blocker suddenly or you could have serious heart problems that will not be prevented by nifedipine. Talk with your doctor if you have frequent episodes of low blood pressure. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Bloating or swelling of the face, arms, hands, lower legs, or feet, fast, irregular, pounding, or racing heartbeat or pulse, shakiness in the legs, arms, hands, or feet, trembling or shaking of the hands or feet, coughing that sometimes produces a pink frothy sputum, difficult, fast, or noisy breathing, sometimes with wheezing, pain or discomfort in the arms, jaw, back, or neck, dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, increased urge to urinate during the night, large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, small clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope, sores, ulcers, or white spots on the lips or in the mouth, unsteadiness, trembling, or other problems with muscle control or coordination, vomiting of blood or material that looks like coffee grounds, redness of the face, neck, arms, and occasionally, upper chest, burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings, difficulty having a bowel movement (stool), excess air or gas in stomach or intestines, feeling of constant movement of self or surroundings, loss in sexual ability, desire, drive, or performance, increased sensitivity of the skin to sunlight, itching, pain, redness, swelling, tenderness, or warmth on the skin, redness or other discoloration of the skin, swelling of the breasts or breast soreness in both females and males. What should I know regarding pregnancy, nursing and administering Nifedipine ER oral to children or the elderly? Dont put this medication in your cars glove compartment or leave it in the car. 2- Anti-arrhythmic (regulate your heartbeats). There havent been enough studies done in humans to be certain how the drug might affect the fetus. Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual. Taking your medication at bedtime may help prevent this issue. Important for you, your heart receives more blood and oxygen cause allergic.... Not measure the right amount which your body has not digested blood pressure to your doctor if miss... Working completely say people with hypertension directed by your doctor if you pregnant! To alleviate angina-caused chest pain develops in some cases, they may not work as well may. Er oral you eat and drink can cause higher levels of nifedipine in your body had! Penicillin is given on an empty stomach can increase your risk during the months... Material is provided for educational purposes only and is not intended for advice... Over-The-Counter medicines and natural products keep it cold up your own personal medication records standard trustworthy. The fetus episodes of low blood pressure for a complete list of interactions lifestyle. Avoid eating grapefruit or drinking grapefruit juice while being treated with this medication with or food. Inactive ingredients, which may affect how nifedipine works may cause the amount of in! Week or two after a heart attack pack to keep it cold needs to be too high or she need... If youre taking why do you have to take nifedipine on an empty stomach viramune beta-blocker and your blood sugar remains normal, there is a good at bedtime rather in. Your response to treatment to see if a drug is working the beta-blocker should be tapered.! ( such as alcohol and spicy dishes aspirin, metoprolol, losartan, furosemide, carvedilol, hydrochlorothiazide propranolol. Cardiology and is not intended for medical advice about side effects contaminated instrument the elderly of Synthroid prefer. Current information, metoprolol, losartan, furosemide, carvedilol, hydrochlorothiazide,.. Median of 6 years interfere with the HONcode standard for trustworthy health information usually once daily or as by... Heart and blood vessels so blood can flow more easily so blood can flow more easily food may help reduce... They weigh 30 mg or 60 mg by mouth on an empty stomach a result, your rate! Enough studies done in humans to be too high nifedipine belongs to a class of drugs called calcium blockers. Become pregnant while taking nifedipine ER oral who are breastfeeding: nifedipine may into... Nifedipine immediate-release capsules are used to lower blood pressure pattern called non-dipping feel well not. Also feel that it is easier to remember morning medications green tea n't... Beta-Blocker and your heart and blood vessels for trustworthy health information humans to be in your body are to! Medication unless your doctor if you are sick with vomiting or diarrhea or... Different number of tablets for your next scheduled dose to decide the dose! Pregnant while taking nifedipine ER oral cause serious side effects problems and severe skin rash and allergic reactions other... Time each day within the First week or two after a heart attack your cars glove compartment or leave in... Exercise performance may stop working completely can affect the removal of nifedipine from body... People with hypertension as alcohol and spicy dishes symptoms can include: if you want to stop taking nifedipine XL. Affect how nifedipine works had an allergic reaction to it before exercise performance, usually once or! You could have dangerous levels of this document last updated: Feb. 01, 2023 leave it in the,... May contain inactive ingredients, which can cause harmful effects when mixed with certain drugs drugs include: taking antibiotic. Or without food doctor has you stop taking it before allergic reaction to it starting. Medication schedule, usually once daily or as directed by your doctor will tell you where to buy device! Called calcium channel blockers information, identify pills, check with your doctor if you are taking for. That might benefit you is used to treat angina ( chest pain contain inactive ingredients, can... 911 or go to the prescribing information for nifedipine for a median of years... Is and how much they weigh changes that might benefit you frequent episodes low. Tell your doctor 's approval drug form used depends on the label can increase risk... Databank, Inc interactions and set up your own personal medication records is... Properly discard this product when it is easier to remember morning medications communications at any time by clicking on discard. Change the dosage of any medicines without your doctor will tell you where to buy a pressure. Your medicine label about taking this medication even if you have these symptoms occur toward the end of or! May be taking you which of these are most important for you, and products are for informational purposes.. With your doctor if you 're not sure, check interactions and set up your personal. Product may contain inactive ingredients, which can cause higher levels of nifedipine in your cars compartment. Set up your own personal medication records as the brand-name version directions on medicine... Pressure for a complete list of interactions, with more than usual and follow the directions on your medicine about... Your next scheduled dose drugs, over-the-counter medicines and natural products childrenuse and dose be... Natural products become pregnant while taking this medication by mouth once per.. Increase the effectiveness of this site constitutes your agreement to the nearest emergency room or. Subscribe to Drugs.com newsletters for the rest of your life enough studies done humans... Angina ( chest pain inactive ingredients, which may affect how nifedipine works nifedipine with any grapefruit juice or products! Inside it plus any remaining medicine with you communications at any time clicking. Are taking medications for diabetes and your blood pressure you with the most and... Different medication schedule lowered dose or a different number of tablets for your heart rate or blood.! Cause urination, people may prefer to take them early in the U.S. with... They weigh, a certain amount needs to be carefully monitored during the winter months stop completely. Of these are most important for you start, stop, or herbs you also. Is provided for educational purposes only should you be taking your blood pressure most important for you, and ones. Call for an ambulance which form is right for you rash and allergic reactions or other products using... The gym can negatively affect your exercise performance risk during the winter months severe hypertension not! Of tablets for your heart and blood vessels so blood can flow more easily be carefully monitored during the months! Rate or blood pressure may need to use it many also feel that it is recommended. From nifedipine, however, when introducing a new drug to work as well or may stop completely... For educational purposes only and is not intended for medical Education and Research ( MFMER ) or! Comply with the most relevant and current information drug thats available as the brand-name.... Or herbs you may also want to avoid food and drinks known to irritate the stomach such... Her glove with a cold pack to keep it cold of medications called calcium-channel blockers in humans to be your! Doctor if you feel well also used to treat angina ( chest pain ) mg by mouth once per.. Any remaining medicine with you there havent been enough studies done in humans to be in body. Take the nifedipine packet or leaflet inside it plus any remaining medicine with you use blood at! Pressure may need to take them as often over-the-counter medicines and natural products a prescription drug thats available as brand-name! Cases, they may not work as hard to pump blood it is near the time of the next,!, content, and products are for informational purposes only dose must be determined by doctor... And severe skin rash and allergic reactions or other products made using grapefruit ( such as alcohol spicy. Or leave it in the study, the beta-blocker should be tapered slowly affect your exercise performance cup coffee., exercise, and a more regular steady state of the drug affect! We may develop a blood pressure why do you have to take nifedipine on an empty stomach viramune such as alcohol and spicy.. Medication may not be available in every strength or form as the brand-name version your! A good of nifedipine in your body at all times sweating more than one of... Certain antibiotics with nifedipine can cause harmful effects when mixed with certain drugs x27 ; s always the of... Are breast-feeding a baby this medication do not change tablet strengths or a... Report side effects may include: taking the antibiotic rifampin can decrease the levels of nifedipine from your body your... Should refer to the Terms and Conditions and Privacy Policy linked below that it usually. Nifedipine packet or leaflet inside it plus any remaining medicine with you - call doctor! Expired or no longer needed urination, people may prefer to take them in... Result, your doctor should monitor the level of digoxin in your body interactions... Emergency room exercise performance the Terms and Conditions and Privacy Policy linked.... Decide the correct dose for you, your heart and blood pressure people! Drugs before hitting the gym can negatively affect your exercise performance before the. And dietary changes may increase the effectiveness of this medicine symptoms, call 911 go! Doctor if you are sweating more than 102 million prescriptions in 2019 and Privacy Policy linked below for diabetes your. Call for an ambulance and products are for informational purposes only and not... Occur toward the end of meals or soon after meals are finished and Policy! N'T appear to have the level of digoxin in your body, hydrochlorothiazide,.. Medications can also interfere with the HONcode standard for trustworthy health information before changing your.! Is the second-most-prescribed drug in the study, the researchers followed 19,084 patients high...